ea0016p11 | Adrenal | ECE2008
Sgro Paolo
, Gallotta Maria Chiara
, Emerenziani Gian Pietro
, Fierro Valentina
, Guidetti Laura
, Baldari Carlo
, Romanelli Francesco
, Lenzi Andrea
, Di Luigi Luigi
Worldwide numerous active individuals take phosphodiesterase type 5 inhibitors (PDE-5i), furthermore, to our knowledge, the effects of these drugs on hormone secretion has not been adequately investigated. In particular, considering that a) PDE-5i influence NO bioavailability, b) NO is one of the mediators of the hypothalamuspituitaryadrenal (HPA) axis response to stress, and, c) physical exercise-related stress activate HPA axis, we investigated whether PDE-5i inf...